Our team

Highly qualified and motivated employees work for you to create a professional prerequisite for your success. Our employees have a sound background and extensive experience.

Helena Sigal
+49 (0)341 962 800-0
Helena Sigal MD, Founder and Owner

Tel: +49 (0)341 962 800-0

E-Mail: kontakt@sigal-sms.de

Helena began her career in the world of clinical research in 2004, as a study physician at the ClinPharm study site in Chemnitz.

The world of clinical research fascinated her from the very beginning. Having the ability to offer more to patients, even in cases of despair, gave her the motivation to continue working and developing herself, her skills and her experience in this area.

In 2008, she took over the position of Director Clinical Operations at the German SMO ClinPharm International GmbH with exclusively dedicated research centres. She was responsible for the clinical processes in eight study sites in Germany and also actively participated in the establishment of new study sites abroad.

After the sale of the German company to the English company Synexus LTD in 2010, she took over the management of the German branch as Director of Operations. She was responsible for about 70 employees. Her new responsibilities included corporate management, human resources, finances and budgeting. She reported directly to senior executives in the UK, where she gained a lot of experience in international management. These tasks expanded her the extensive clinical, study and operative knowledge.

In May 2014, she decided to share her knowledge and expertise with private physicians who conducted studies in their own practices in Germany. Established physicians have tremendous potential to carry out clinical trials, qualitatively and quantitatively, at the highest level. This is due to their high professional qualifications and the long-term relationship that they have with their patients. However, they need professional support for the organizational elements of study sites and their consistency in all their assignments. That's how an idea was born.

After the first positive talks with some colleagues, the time had come. The network was born…

Today, Helena Sigal leads a young, successful and highly motivated team, which works proactively, creatively and solution-oriented which she is very proud of.

The network currently includes around 30 study sites in Germany and new ones are constantly being added.
Denise Aumer
+49 (0)341 962 800-13
Dr. Denise Aumer Clinical Operations Manager

Tel: +49 (0)341 962 800-13

E-Mail: denise.aumer@sigal-sms.de

Michaela Hottenrott
+49 (0)341 962 800-23
Dr. Michaela Hottenrott Feasibility Supervisor & Project Management Assistant

Tel: +49 (0)341 962 800-23

E-Mail: michaela.hottenrott@sigal-sms.de

Find out more about Michaela Hottenrott D

At SIGAL SMS GmbH, Michaela is responsible for the professional control of the central feasibility process and the project management of the individual trials. She works closely with our network partners, helping them with emerging issues that can arise during the course of the studies to develop productive solutions with them. She also oversees patient recruitment and support, project-based financial planning and quality control of each project.


Nicole Zimmer
+49 (0)341 962 800-18
Nicole Zimmer Project Manager

Tel: +49 (0)341 962 800-18

E-Mail: nicole.zimmer@sigal-sms.de

Nadine Hösler
+49 (0)341 962 800-15
Dr. Nadine Hösler Feasibility & Project Management Assistant

Tel: +49 (0)341 962 800-15

E-Mail: nadine.hoesler@sigal-sms.de

Candy Jesche
+49 (0)341 962 800-17
Candy Jesche Patients Recruitment Assistant

Tel: +49 (0)341 962 800-17

E-Mail: candy.jesche@sigal-sms.de

Find out more about Candy Jesche D

Candy oversees patient recruitment at SIGAL SMS GmbH. She uses her professional experience, gained from working in the pharmaceutical industry, in the development & implementation of recruitment concepts. Our network partners benefit from various creative and innovative recruitment options and constant evaluation and optimization of individual recruiting methods. Candy works closely with our study sites and supports them in patient acquisition with printed media, on social media, online marketing and even in the design of advertisements.

Bärbel Siebert
+49 (0) 151 16 74 72 03
Bärbel Siebert Site Network Specialist

Tel: +49 (0) 151 16 74 72 03

E-Mail: baerbel.siebert@sigal-sms.de

Find out more about Bärbel Siebert D

Bärbel is in direct contact with our network partners of the »old« federal states of Germany and thus also responsible for the further development and growth of the company. She ensures the continuous care of existing and new study sites and supports them in many various areas. Her experience is based on several years as a practice manager and as a field service representative for patient recruitment of a study site. Now she ensures a smooth flow of information between the respective employees and our network partners at SIGAL SMS GmbH.

Angela Hübner
+49 (0) 176 21 60 74 80
Angela Hübner Site Network Specialist

Tel: +49 (0) 176 21 60 74 80

E-Mail: angela.huebner@sigal-sms.de

Find out more about Angela Hübner D

Angela acts as our contact person at SIGAL SMS GmbH for our network partners in the »new« states of Germany and facilitates the communication between the physicians and our team. For newcomers to our network or physicians, who want to open up a new area of activity with the implementation of clinical trials, Angela is at their side for all challenges from the very beginning and provides support and care for them, for example, in recruitment, in patient acquisition and in many other areas.

Jeanny Richter
+49 (0)341 962 800-12
Sarah Schwerdtfeger
+49 (0)341 962 800-13
Sarah Schwerdtfeger

Tel: +49 (0)341 962 800-13

E-Mail: sarah.schwerdtfeger@sigal-sms.de

Melanie Domin
+49 (0)341 962 800-14
Melanie Domin Finance Controller

Tel: +49 (0)341 962 800-14

E-Mail: melanie.domin@sigal-sms.de

Find out more about Melanie Domin D

As well as being a graduate in business administration, Melanie has many years of experience in the areas of annual financial audit, corporate valuation, start-up and consolidation consulting as well as the preparation and creation of business plans and feasibility analyses. As a freelance consultant, at SIGAL SMS GmbH, she is responsible for controlling and for the management of all financial processes including costs and budget planning and financial accounting. She advises the management on all pending operational and strategic corporate planning.

Anja Meinelt
+49 (0)341 962 800-21
Antje Wittich
+49 (0)341 962 800-24
Antje Wittich Head of Marketing & Patient Outreach

Tel: +49 (0)341 962 800-24

E-Mail: antje.wittich@sigal-sms.de